Articles

In the current era of escalating atmospheric CO2 levels and its concomitant exacerbation of the greenhouse effect, the search for innovative, sustainable solutions to mitigate these impacts is urgent, particularly in addressing the global challenge of nutrient production. This study explores the potential of using captured carbon dioxide as a dual resource for mitigating climate change and developing nutrients and food. Specifically, we investigate the use of Rhodotorula mucilaginosa UANL-001L to convert CO2 captured from a CO2-enriched atmosphere into carotenoids. This process involves cultivating R. mucilaginosa UANL-001L on Synechocystis sp. PCC 6803 biomass, itself produced from an enriched CO2 source. Our findings reveal that a 30-day cultivation period under these conditions leads to the production of 1 g/L of reducing sugars from the Synechocystis sp. PCC 6803 biomass. The efficiency of sugar …

Influenza poses a substantial health risk, with infants and the elderly being particularly susceptible to its grave impacts. The primary challenge lies in its rapid genetic evolution, leading to the emergence of new Influenza A strains annually. These changes involve punctual mutations predominantly affecting the two main glycoproteins: Hemagglutinin (HA) and Neuraminidase (NA). Our existing vaccines target these proteins, providing short-term protection, but fall short when unexpected pandemics strike. Delving deeper into Influenza's genetic makeup, we spotlight the nucleoprotein (NP) - a key player in the transcription, replication, and packaging of RNA. An intriguing characteristic of the NP is that it is highly conserved across all Influenza A variants, potentially paving the way for a more versatile and broadly protective vaccine. We designed and synthesized a novel NP-Hoc fusion protein combining Influenza A …

Antimicrobial resistance is a global health threat. Misuse and overuse of antimicrobials are the main drivers in developing drug-resistant bacteria. The emergence of the rapid global spread of multi-resistant bacteria requires urgent multisectoral action to generate novel treatment alternatives. Combination therapy offers the potential to exploit synergistic effects for enhanced antibacterial efficacy of drugs. Understanding the complex dynamics and kinetics of drug interactions in combination therapy is crucial. Therefore, this review outlines the current advances in antibiotic resistance's evolutionary and genetic dynamics in combination therapies-exposed bacteria. Moreover, we also discussed four pivotal future research areas to comprehend better the development of antibiotic resistance in bacteria treated with combination strategies.

As the global urgency for effective antimicrobial agents intensifies, this work harnesses the widely demonstrated antimicrobial activity of silver nanoparticles (Ag-NPs) and proposes alternative synthesis approaches to metal–organic hybrid systems with antimicrobial activity. In this study, the proposed synthesis route involves decorating metallic nanoparticles into organic substrates without previous doping. The synthesis simultaneously uses polyethylene glycol for three crucial purposes: (1) acting as a mild reducing agent to generate Ag-NPs with a spherical shape and diameters ranging from 10 to just over 20 nm, (2) functioning as a dispersing agent for flakes of commercial nanostructured carbon supports, including reduced graphene oxide (rGO, ID-nano), and commercial carbon nanoplatelets from Sigma-Aldrich (GNPs, Sigma-Aldrich), and (3) serving as a promoter for the homogeneous anchoring of Ag-NPs in …

Nuevo León, situado en una región semiseca al norte de México, enfrenta periodos de sequía recurrentes, agravados por el crecimiento poblacional. La escasez de agua se convierte en un desafío crítico para la región, ya que la dependencia de presas y reservas es afectada por factores como la radiación solar, viento, baja humedad relativa y el diseño de los embalses, contribuyendo a pérdidas significativas por evaporación. Este artículo aborda la problemática proponiendo diversos métodos para reducir las tasas de evaporación, como monocapas de alcoholes grasos, shade balls, sistemas modulares flotantes, paneles fotovoltaicos flotantes, así como coberturas flotantes y suspendidas. La implementación de estas tecnologías se examina a la luz de experiencias exitosas en otros países, destacando su potencial para optimizar la gestión del agua en Nuevo León y ofrecer soluciones sostenibles ante los desafíos climáticos y de crecimiento demográfico.